Commentary on Meditations: B5:10

Realities are wrapped in such a veil (as it were) that several philosophers of distinction have thought them altogether beyond comprehension, while even the Stoics think them hard to comprehend. And every assent we may give to our perceptions is fallible: the infallible man does not exist. Pass, then, to the very objects of our experience - how short-lived they are, how shoddy: a catamite, a whore, a thief could own them. Go on now to the characters of your fellows: it is hard to tolerate even the best of them, not to speak of one's difficulty in enduring even oneself.

In all this murk and dirt, in all this flux of being, time, movement, things moved, I cannot begin to see what on earth there is to value or even to aim for. Rather the opposite: one should console oneself with the anticipation of natural release, not impatient of its delay, but taking comfort in just these two thoughts. One, that nothing will happen to me which is not in accordance with the nature of the Whole: the other, that it is in my control to do nothing contrary to my god and the divinity within me - no one can force me to this offence.

We may worry and add our opinion on many things and we may be wrong about our perceptions.  We need to understand that we are fallible and prone to mistakes.

Furthermore, we need to realize this life is short-lived.  And it is full of ornery people, including ourselves.

Marcus finds little to no value in all this.  One ought to console oneself that we will naturally be released from this life, according to nature.